MHRA Heatwave Warning: Antibiotics, Diuretics, Antidepressants Risks
MHRA Issues Heatwave Warning for Common Medications

The Medicines and Healthcare products Regulatory Agency (MHRA) has issued crucial guidance for individuals taking antibiotics, diuretics, or antidepressants as the UK experiences temperatures exceeding 30 degrees Celsius. Hot weather can alter how the body responds to medications, potentially affecting those managing long-term conditions. However, simple precautions can mitigate risks.

Medication Storage and Sun Sensitivity

Alison Cave, MHRA's Chief Safety Officer, emphasized that medicines left in hot environments like cars, bags, or sunny windowsills may become ineffective. Some common drugs, including certain antibiotics, diuretics, antidepressants, and skin treatments for acne or eczema, can increase skin sensitivity to sunlight, leading to burns even in mild sunshine. Painkillers like ibuprofen or naproxen may also cause mild sun sensitivity, particularly with frequent or long-term use.

Special Warning for Methotrexate Users

Methotrexate, used for rheumatoid arthritis, psoriasis, Crohn's disease, and cancer, requires extra caution. It can cause extreme sun sensitivity, resulting in painful rashes, blistering, or swelling resembling severe sunburn, with rare instances leading to serious infections. The risk rises during sunny weather, even with brief outdoor activities like walking the dog or gardening.

Wide Pickt banner — collaborative shopping lists app for Telegram, phone mockup with grocery list

Practical Advice from Pharmacists

Well Pharmacy UK advises on TikTok to check medication storage instructions, keep drugs out of direct sunlight, stay hydrated, and protect skin with SPF, shade, and light clothing. Alison Cave recommends storing medicines in a cool, dry place away from sunlight, recognizing signs of heat-related illness, and consulting healthcare professionals if questions arise.

Medical Devices Also at Risk

The MHRA notes that medical devices, such as blood glucose monitors, can be affected by heat or humidity, potentially giving less reliable readings. Users should keep devices and test strips in a cool, dry location and follow temperature guidance in instructions. If a device malfunctions, a control check or pharmacist advice is recommended.

Pickt after-article banner — collaborative shopping lists app with family illustration